Enalapril Maleate
Paşî
Enalapril Maleate
Terîf
Enalapril (maleate) (MK-421 (maleate)), metabolîta çalak a enalapril, înhîbîtorek enzîma veguherîner a angiotensin (ACE) ye.
In Vivo
Enalapril (MK-421) prodermanek e ku ji çîna dermanên înhîbîtorê enzîma veguherîna angiotensin (ACE) ye.Piştî rêveberiya devkî, ew di kezebê de zû metabolize dibe enalaprilat.Enalapril (MK-421) astengkerek bihêz û pêşbazker a ACE ye, enzîma ku berpirsiyarê veguhertina angiotensin I (ATI) bo angiotensin II (ATII) ye.ATII tansiyona xwînê sererast dike û hêmanek bingehîn a pergala renin-angiotensin-aldosterone (RAAS) e.Enalapril dikare ji bo dermankirina hîpertansiyonek bingehîn an renovaskuler û têkçûna dil a nîşankirî were bikar anîn.
Embarkirinî
Toz | -20°C | 3 sal |
4°C | 2 sal | |
Di solvent de | -80°C | 6 meh |
-20°C | 1 Meh |
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